Chief Commercial Officer / Chief Revenue Officer

Ossium Health

Ossium Health

San Francisco, CA, USA
USD 275k-375k / year + Equity
Posted on Jul 8, 2025

Ossium Health is a clinical-stage bioengineering company dedicated to improving human health, vitality, and longevity through innovative stem cell-based therapies and bone marrow banking. Our goal is to revolutionize healthcare by leveraging cutting-edge biotechnology to treat blood cancers, enhance organ transplantation, and repair damage from radiation. Headquartered in San Francisco, CA, with a state-of-the-art facility in Indianapolis, IN, Ossium collaborates with healthcare providers, life science companies, and organ procurement organizations to deliver transformative cell therapies.

Position: Chief Commercial Officer / Chief Revenue Officer (CCO/CRO)
Location: San Francisco, CA
Reports to: Kevin Caldwell, CEO, Co-Founder & President
Type: Full-Time

Position Summary

Ossium Health is seeking an experienced and dynamic Chief Commercial Officer / Chief Revenue Officer (CCO/CRO) to serve as a strategic partner to the CEO and drive the company’s commercial and operational success. The CCO/CRO will lead the scaling of Ossium’s commercial operations, overseeing sales, marketing, business development, and strategies to achieve commercial revenue growth to a target of over $1B at peak. This role requires a proven leader with deep expertise in building and scaling medical device or biotechnology companies, a track record of driving significant revenue growth, and the ability to navigate complex healthcare ecosystems. This position is based in our San Francisco office; we maintain a hybrid schedule of Monday - Thursday in the office, with Friday as a remote work day

Key Responsibilities

  • Strategic Leadership: Partner with the CEO, executive team, and Board of Directors to develop and execute Ossium’s strategic vision, aligning commercial objectives with the company’s mission to improve human health through bioengineering.
  • Commercial Strategy and Execution: Design and implement a comprehensive commercial strategy, including market access, sales, and marketing initiatives for Ossium’s bone marrow-derived cell therapy platform. Drive revenue growth to achieve targets.
  • Team Leadership and Development: Build, mentor, and lead a high-performing commercial team, fostering a culture of excellence, innovation, and collaboration.
  • Financial and Performance Management: Develop and manage commercial team budgets, forecasts, and key performance metrics.

Required Qualifications

  • Experience:
    • 15+ years of commercial leadership experience in the medical device, biotechnology, or pharmaceutical industries, with a proven track record of scaling a company as outlined above
    • Demonstrated success in building and leading commercial functions in a high-growth, clinical-stage biotech or medical device company
    • Extensive experience in market access, product commercialization, and strategic partnerships within the healthcare ecosystem
  • Education:
    • Bachelor’s degree in business, life sciences, or a related field required; advanced degree (MBA, MD, or PhD) strongly preferred
  • Skills and Competencies:
    • Strategic thinker with the ability to translate vision into actionable plans and measurable results
    • Deep understanding of cell therapy, biologics, or medical device markets, including regulatory and reimbursement landscapes
    • Exceptional leadership and team-building skills, with a track record of fostering collaboration and innovation in high-growth environments
    • Strong business acumen with experience managing budgets, and P&L

Preferred Qualifications:

  • Experience building new commercial assets
  • Management consulting experience
  • Established network within the biopharmaceutical, healthcare, or life sciences industries

Why Join Ossium Health?

  • Be a key leader in a mission-driven company revolutionizing bioengineering to improve human health and longevity
  • Work alongside a passionate, innovative team, including industry leaders like Kevin Caldwell and Dr. Erik Woods, in a collaborative and high-growth environment
  • Contribute to groundbreaking work, such as the PRESERVE I clinical study and the Ossium HOPE Program, that address critical unmet needs in blood cancer treatment
  • Join a company recognized as one of Forbes’ Best Startup Employers and Fast Company’s 100 Best Workplaces for Innovators

This position has a compensation range of $275,000 - $375,000 annually. Ossium Health takes a market-based approach to pay. The successful candidate’s starting salary will be determined based on, but not limited to, job-related skills, experience, qualifications, and market conditions. This range may be modified in the future.

We offer a full slate of employee benefits including:

  • Stock options
  • 401(k) matching
  • Medical, dental and vision coverage
  • Four weeks of PTO accrued (vacation & sick time) annually + 11 company holidays
  • Employer paid life insurance and long term disability
  • Gym membership/recreational sports reimbursements
Ossium Health provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, sex, national origin, age, disability, protected veteran status, sexual orientation, gender identity, gender expression, or any other protected characteristic. Our Equal Employment Opportunity Policy Statement and the Know Your Rights: Workplace Discrimination is Illegal Poster reaffirm this commitment. Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records.
If reasonable accommodation is needed, please contact our People Team at careers@ossiumhealth.com or 650-285-0603. Ossium Health complies with federal and state disability laws and makes reasonable accommodations for applicants and candidates with disabilities.
Principals / direct applicants only please. Recruiters, please do not contact this job poster.
Equal Opportunity Employer/Veterans/Disabled