The Position:

As the Program Leader for our APOL1 program, you will be at the helm, driving the program vision, strategy, and execution forward. You will oversee resources, budgets and activities ensuring that the program deliverables stay on track as we work toward bringing this important therapy to patients. In this role, your leadership will be critical in making key decisions, collaborating with the program team and functional leaders, and integrating their input into the program’s development.

Reporting directly to our Chief Strategy and Business Officer, you’ll manage the APOL1 Project Manager and play a central role in steering the program towards its goals.

Your Impact:

• Develop and execute program strategy that aligns with our program vision, guiding cross-functional teams through milestones and decision points.
• Communicate a clear program strategy, ensuring alignment across all functions and its reflection in every step of execution.
• Lead one or more Program teams comprised of experts in clinical development, clinical operations, manufacturing, and regulatory affairs to deliver high-quality, compliant, and on-budget outcomes.
• Develop a compelling, forward-thinking strategy by leveraging prior knowledge and experience, and discernment of external stakeholders, internal team capabilities, and program needs.
• Prioritize and allocate resources effectively to meet program needs while ensuring rigorous adherence to quality and compliance.
• As the single point of accountability, drive key decisions and navigate them through appropriate governance channels.

As a Vice President, we also expect our leaders to demonstrate the following Leadership Competencies:

• Communication and Influence
  • Communicates strategic vision and enterprise priorities through compelling examples, stories, and presentations.
  • Aligns successfully with other senior leaders to influence strategies, priorities, and roadmap.
  • Leads large-scale initiatives that result in meaningful change within their organization.
• Teamwork and Collaboration
  • Recognizes competing priorities and brings people together to ensure cross-functional alignment and connection.
  • Builds internal community by driving cross-company initiatives focused on culture and employee engagement.
• Execution and Results
  • Demonstrates accountability for overall results within their organization.
  • Manages risk and long-term investment while prioritizing Maze over functions.
  • Takes a longer-term view of the business/market and proactively identifies the largest opportunities and risks inhibiting future growth.
• Develop Others and Self
  • Inspires, grows, and retains senior leaders through internal development.
  • Holds direct-reports accountable for identifying and developing talent.
  • Obtains resources needed to support development initiatives.

Skills and Qualifications:

• Relevant degree is required; a doctorate or other advanced degree is preferred, with 7-10+ years of experience in drug development. This should include leading Program Teams through late-stage development, and preferably through market access with clinical experience.
• Extensive experience in drug development, particularly in renal or related disease areas.
• Demonstrated ability to lead cross-functional multidisciplinary teams effectively.
• Strong understanding of clinical trials, regulatory processes, technical operations, market access, and commercialization.
• Direct experience with product registration and major health authority interactions with a preference for commercialization experience.
• A strategic, innovative thinker with a robust external network
• Willingness and ability to work onsite at our South San Francisco facility.

About Maze Therapeutics

Maze Therapeutics is a biopharmaceutical company that is harnessing the power of human genetics to transform the lives of patients, with a focus on genetically informed therapies for common diseases, such as chronic kidney disease, and seeks to focus expertise and resources towards underserved communities. Maze applies variant functionalization in tandem with advanced data science methods and a robust suite of research and development capabilities to advance a pipeline of novel precision medicines. Maze has developed the Maze Compass Platform™, a proprietary, purpose-built platform to understand and integrate the critical step of variant functionalization into each stage of drug development. Utilizing the Maze Compass Platform™, Maze is building a broad portfolio of wholly owned and partnered programs. Its two lead programs are focused in Chronic Kidney Disease (CKD), a condition that impacts an estimated 37m individuals. The first program in CKD addresses a genetic subset of the common disease that has a disproportionate impact on the Black Community. Maze is based in South San Francisco.

Our People

Maze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases. We are fostering a culture that encourages vision, initiative and the development of talent. Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work. While we have a passion for advanced science and pride ourselves on excellence in execution, ultimately, everything we do is about patients.

Our Core Values

Further Together – Our path is paved with challenges, but with resilience and a team-first mentality, we’ll achieve our mission.

Impact Obsessed – We embrace the bold, take calculated risks, and learn from our mistakes to improve the lives of others.

Stand True – Our integrity is foundational; it guides us no matter the obstacle.

The expected annual salary range for employees located in the San Francisco Bay Area is $276,000 - $338,000. Additionally, this position is eligible for an annual performance bonus. Maze performs position-based compensation benchmarking to industry market data to ensure we pay competitive wages. Determination of starting salary will depend upon a variety of job-related factors, which may include professional experience, skills, and job location. The expected salary range for this role may be modified in the future.

Maze offers a robust benefits package to our eligible employees including competitive medical, dental, and vision insurance, mental health offerings, equity incentive plan, 401(k) program with employer match and a generous holiday and PTO policy.