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Research Associate, In Vivo Pharmacology

Maze Therapeutics

Maze Therapeutics

South San Francisco, CA, USA
Posted on Saturday, May 25, 2024

The Position:

Are you driven by a passion for scientific discovery and a desire to make a tangible impact on human health? We're seeking a passionate, creative, and dedicated Research Associate to join our in vivo pharmacology team. In this role, you will be pivotal in conducting pharmacokinetic studies that drive our research projects forward, while also contributing to preclinical pharmacodynamic and disease models. Under the guidance of the Director of Pharmacology, your work will directly support the discovery of new drug candidates and advance our understanding of disease mechanisms. Additionally, as a rapidly growing biotech company, we offer an exciting and collaborative work environment where every team member plays a vital role in our success.

Your Impact:

  • Conduct in vivo preclinical pharmacokinetic (PK) studies and contribute to in vivo pharmacodynamic (PD) studies investigating target engagement or efficacy in disease models to support drug candidate discovery
  • Work closely with Maze’s bioanalytical group and other project team members to assist in coordinating PK/PD studies
  • Record and analyze data using Microsoft Excel, Word, GraphPad Prism, and specialized laboratory software, ensuring accuracy and clarity
  • Present results at group and department meetings

Skills and Qualifications:

  • Bachelors degree in biology, pharmacology, or other relevant field is required
  • At least one year of experience in in vivo pharmacokinetic or pharmacology studies in a pharmaceutical company
  • High proficiency in rodent dosing via multiple routes of administration
  • Biological sample collection for pharmacokinetic analysis is essential
  • Ability to conduct routine in vivo studies with a commitment to high-quality work, and fluency with general biology lab procedures
  • Capacity to learn and understand new laboratory technologies and techniques, with the flexibility to support high priority tasks or projects
  • Excellent communication skills and ability to work effectively in a team-based environment
  • Extremely detail oriented and highly organized, with a strong sense of pride in the quality of your work
  • Adherence to corporate polices for maintaining electronic lab notebook (ELN) records, working safely in laboratory environment, and ensuring compliance with animal welfare regulations

About Maze Therapeutics

Maze Therapeutics is a biopharmaceutical company that is harnessing the power of human genetics to transform the lives of patients, with a focus on genetically informed therapies for common diseases, such as chronic kidney disease, . and seeks to focus expertise and resources towards underserved communities. Maze applies variant functionalization in tandem with advanced data science methods and a robust suite of research and development capabilities to advance a pipeline of novel precision medicines. Maze has developed the Maze Compass Platform™, a proprietary, purpose-built platform to understand and integrate the critical step of variant functionalization into each stage of drug development. Utilizing the Maze Compass Platform™, Maze is building a broad portfolio of wholly owned and partnered programs. Its two lead programs are focused in Chronic Kidney Disease (CKD), a condition that impacts an estimated 37m individuals. The first program in CKD addresses a genetic subset of the common disease that has a disproportionate impact on the Black Community. Maze is based in South San Francisco.

Our People

Maze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases. We are fostering a culture that encourages vision, initiative and the development of talent. Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work. While we have a passion for advanced science and pride ourselves on excellence in execution, ultimately, everything we do is about patients.

Our Core Values

Further Together – Our path is paved with challenges, but with resilience and a team-first mentality, we’ll achieve our mission.

Impact Obsessed – We embrace the bold, take calculated risks, and learn from our mistakes to improve the lives of others.

Stand True – Our integrity is foundational; it guides us no matter the obstacle.

The expected annual salary range for employees located in the San Francisco Bay Area is $76,000 to $92,000. Additionally, this position is eligible for an annual performance bonus.

Maze performs position-based compensation benchmarking to industry market data to ensure we pay competitive wages. Determination of starting salary will depend upon a variety of job-related factors, which may include professional experience, skills, and job location. The expected salary range for this role may be modified in the future.

Maze offers a robust benefits package to our eligible employees including competitive medical, dental, and vision insurance, mental health offerings, equity incentive plan, 401(k) program with employer match and a generous holiday and PTO policy.