Senior Technical Program Manager, Platform

Lila Sciences

Lila Sciences

IT, Operations
Cambridge, MA, USA
Posted on Feb 7, 2026

Your Impact at Lila

We are hiring a Senior Technical Program Manager (TPM) to lead high-impact, cross-functional programs spanning software engineering, security, IT, labs, and AI teams. This person will drive the planning, execution, and delivery of our compliance roadmap, including FedRAMP readiness and other certifications required to support government and regulated deployments.

In parallel, this role will run critical software platform programs that improve delivery, reliability, security posture, developer velocity, and operational excellence across our platform.

What You'll Be Building

  • Own the end-to-end program plan for FedRAMP readiness and adjacent compliance certifications (e.g., SOC 2, ISO 27001, HIPAA as applicable), including milestones, dependencies, resourcing, and executive reporting.
  • Build and run the cross-functional operating rhythm: program reviews, risk/issue management, decision logs, and stakeholder communications across software, security, IT, labs, and AI teams.
  • Partner with Security/GRC to translate compliance requirements into implementable workstreams (controls, evidence collection, tooling, process changes) with clear owners and timelines.
  • Drive remediation programs for gaps identified via audits, penetration tests, control assessments, and operational incidents.
  • Write technical documentation, diagrams, and evidence readiness, including system boundaries, SSP inputs, policies/standards, and traceability from requirements to artifacts.
  • Manage external-facing and 3rd party dependencies (assessors, auditors, vendors) and ensure internal teams are prepared for interviews and evidence requests.
  • Run software platform programs that span multiple engineering teams
  • Establish program-level metrics and continuously improve execution through retrospectives and process refinement.
  • Identify and resolve organizational bottlenecks by clarifying ownership, simplifying interfaces, and driving crisp decision-making.
  • Create artifacts that scale: roadmaps, one-pagers, architecture/controls narratives, runbooks, and status updates tailored to technical and executive audiences.

What You’ll Need to Succeed

  • 8+ years of technical program management, engineering program management, or equivalent experience delivering complex, cross-functional software and infrastructure programs.
  • Demonstrated experience leading compliance, security, or audit-adjacent programs in cloud and software environments (FedRAMP experience is a strong plus).
  • Strong working knowledge of modern cloud and software delivery systems (AWS, identity, networking, infrastructure, CI/CD, observability, SDLC).
  • Proven ability to translate ambiguous requirements into an executable plan with clear milestones, owners, and measurable outcomes.
  • Excellent stakeholder management skills, including aligning teams with different incentives and constraints (engineering, security, IT, and lab operations).
  • Strong written and verbal communication, with the ability to produce concise documentation and executive-ready status updates.
  • Track record of driving programs to completion in fast-moving environments with high standards for quality and security.

Bonus Points For

  • Direct experience with FedRAMP Moderate/High readiness, authorization processes, and the practical implementation of NIST 800-53 controls.
  • Experience with SOC 2 and/or ISO 27001 programs, including control mapping, evidence design, and audit execution.
  • Familiarity with security tooling and practices: IAM, secrets management, endpoint management, vulnerability management, SIEM/logging, and incident response.
  • Ability to operate at multiple altitudes: deep in execution details when needed, while maintaining a clear narrative and roadmap for leadership.
  • Experience building program management frameworks, templates, and repeatable operating rhythms across an organization.

About Lila

Lila Sciences is the world’s first scientific superintelligence platform and autonomous lab for life, chemistry, and materials science. We are pioneering a new age of boundless discovery by building the capabilities to apply AI to every aspect of the scientific method. We are introducing scientific superintelligence to solve humankind's greatest challenges, enabling scientists to bring forth solutions in human health, climate, and sustainability at a pace and scale never experienced before. Learn more about this mission at www.lila.ai

If this sounds like an environment you’d love to work in, even if you only have some of the experience listed below, we encourage you to apply.

Compensation

We expect the base salary for this role to fall between $192,000 – $256,000 USD per year, along with bonus potential and generous early equity. The final offer will reflect your unique background, expertise, and impact.

We’re All In

Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy.

A Note to Agencies

Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto.