Senior ML Engineer
Kouper
This job is no longer accepting applications
See open jobs at Kouper.See open jobs similar to "Senior ML Engineer" General Catalyst.Software Engineering, Data Science
New York, NY, USA
USD 170k-190k / year
Posted on Mar 6, 2026
About Kouper Health
Kouper is redefining how care transitions happen. Backed by General Catalyst, CVS Health Ventures, 25madison, and leading health system partners, we’re on a mission to bridge the care transition gap and fundamentally improve the patient experience — helping people live longer, healthier lives.
Position Overview:
We're looking for a Senior ML Engineer to build the AI systems that power personalized patient engagement at scale. You'll develop and optimize LLM-based applications, build predictive models for patient outcomes, and create the evaluation frameworks that ensure our AI delivers on its promise. This is a foundational role where you'll shape how we apply machine learning to transform healthcare.
Responsibilities
- Design and build LLM-powered applications for patient communication and care navigation
- Develop predictive models for patient engagement, risk stratification, and care optimization
- Build robust evaluation frameworks and metrics to measure model quality, safety, and clinical appropriateness
- Architect ML systems that handle diverse healthcare data sources while maintaining privacy and compliance
- Optimize model performance for latency, cost, and quality across production workloads
- Collaborate with product and clinical teams to translate healthcare problems into ML solutions
- Stay current on ML research and bring relevant innovations into production applications
- Partner with backend engineers to integrate ML systems into the broader platform architecture
Qualifications
- 5+ years of experience in machine learning engineering with at least 2 years working with LLMs or NLP systems
- Strong proficiency in Python and ML frameworks (PyTorch, TensorFlow, Hugging Face)
- Hands-on experience building and deploying LLM-based applications in production
- Deep understanding of modern ML techniques: fine-tuning, prompt engineering, RAG, embedding models
- Experience designing evaluation frameworks and metrics for ML system quality
- Strong software engineering fundamentals with ability to write production-quality code
- Excellent problem-solving skills and ability to translate ambiguous requirements into technical solutions
Preferred Qualifications
- Experience with healthcare AI applications or clinical NLP
- Background in conversational AI, dialogue systems, or voice-based applications
- Research experience or publications in ML/NLP
- Familiarity with healthcare data standards (HL7, FHIR) and privacy requirements (HIPAA)
- Experience with ML infrastructure and MLOps (model serving, monitoring, feature stores)
What We Offer
- Competitive salary and equity package
- Flexible work environment and remote options
- Comprehensive health, dental, and retirement benefits
- The chance to make a significant impact in a mission-driven startup focused on transforming patient care
- Location: NYC, SF, or Remote
- Expected Start Date: Feb 2026
170000 - 190000 USD a year
This job is no longer accepting applications
See open jobs at Kouper.See open jobs similar to "Senior ML Engineer" General Catalyst.
