CTRL Therapeutics Head of Research Remote · Full time

Apply for Head of Research

About us:

We are building a new company to transform the cell therapy space by enabling the rapid generation of effective therapies for patients with solid tumors. We are building a company culture based on collaboration, transparency, integrity, and commitment to excellence. We are looking for passionate people to be a part of this journey.

Location:

Chicago preferred; Will consider remote if located in San Francisco, Boston, Seattle or San Diego, with frequent travel to Chicago.

What you'll do:

We are seeking a highly motivated and experienced Head of Research to lead our research team in developing and optimizing novel circulating tumor-reactive lymphocyte-based therapies. You will play a leadership role in the company and will work closely with the executive team to establish our R&D infrastructure and capabilities. You will directly lead and oversee an internal team of scientists and provide insights, guidance, oversight, and mentorship to the team to ensure the establishment of a quality and data-driven organization that will deliver on corporate objectives. You will bring a strong scientific background in biology, immunology, analytical assessment, and the translation of preclinical science to the development of T-cell therapy products. Additionally, you will bring exceptional leadership, management, operational, and interpersonal skills to this role.

Reporting line:

Reports to the CEO

Specific Responsibilities:

• Build, oversee, and guide research efforts to establish a quality and data-driven organization that delivers on corporate objectives and priorities
• Ensure quality of all laboratory operations, data, analyses, and reports conforms to GLP and statistical and quality principles to enable robust and statistical evaluation of R&D data for presentation and cross-functional discussion, and decision-making
• Design and manage key in vivo and in vitro IND-enabling studies for cell therapy clinical candidates
• Collaborate closely with CTRL’s process development and clinical development teams over time, to integrate translational research into the overall goals of the company
• Play a critical role in external collaborations and partner interactions, evaluations, and diligence
• Represent the company to external stakeholders, scientific meetings and including current and prospective investors
• Collaborate with leadership and management teams to create and maintain a dynamic cross-functional, and effective organization
• Maintain a high level of professional expertise through regular consulting of scientific literature

You should have:

• MD and/or Ph.D. with 7+ years of related experience in Cellular therapy, T cell Immunology, Cellular Biology, or Immunotherapy
• Prior experience in the translation of scientific research concepts to an emerging biopharma setting
• Experience and expertise with the development and application of T cell, functional and analytic assays required, including flow-cytometry, in vitro, and high-throughput molecular characterization
• Experience with GLP processes and guidelines
• Strong scientific and technical expertise in immunology and cell therapy, including knowledge of cellular immunology, CAR-T cell therapies, and adoptive cell transfer methods
• Cell therapy experience would ideally include TILs and/or solid tumors
• Successful track record of effectively managing and mentoring scientific staff (e.g. Ph.D., Research Associates)
• Experience with development and maintaining timelines and budgets for therapeutics development programs
• Ability to work in a fast-paced, collaborative environment and manage multiple concurrent projects with a high degree of independence required
• Experience in both large and emerging biopharmaceutical companies is preferred
• Strong leadership, interpersonal, written, and oral communication skills are required
• A strong drive to inspire, empower, and enable your colleagues to bring the next generation of transformative cell therapies to patients

What we offer:

Compensation: A competitive salary in addition to equity.

Benefits: Health, Dental, and Vision insurance, FHA, 401(k), commuter benefits

At CTRL, we embrace the different backgrounds, perspectives, and experiences our team members bring to the table. As a proud Equal Opportunity Employer, we welcome all applicants and teammates regardless of race, color, ancestry, national origin, religion or religious creed, mental or physical disability, medical condition, genetic information, sex (including pregnancy, childbirth, and related medical conditions), sexual orientation, gender identity, gender expression, age, marital status, military or veteran status, citizenship, or other characteristics protected by applicable law. If you need assistance or an accommodation due to a disability, please contact us.