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Senior Scientist, In Vivo Pharmacology

Altos Labs

Altos Labs

San Francisco, CA, USA
Posted on Saturday, June 29, 2024

Our Mission

Our mission is to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and the disabilities that can occur throughout life.

For more information, see our website at

Our Value

Our Single Altos Value: Everyone Owns Achieving Our Inspiring Mission.

Diversity at Altos

We believe that diverse perspectives are foundational to scientific innovation and inquiry.

We are building a company where exceptional scientists and industry leaders from around the world work side by side to advance a shared mission.

Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives.

At Altos, we are all accountable for sustaining a diverse and inclusive environment.

What You Will Contribute To Altos

An exciting opportunity is available for a Sr. Scientist to join the In Vivo Pharmacology & Biomarker Discovery team of the Institute of Medicine (IOM) at Altos Labs. We are seeking a highly skilled, self-motivated and talented scientist to lead and execute in vivo preclinical research and biomarker discovery activities supporting portfolio progression. The successful candidate will work collaboratively with leading researchers from the Institutes of Science (IOS), our technology hubs, and members of the Institute of Medicine (IoM) to think strategically, lead and execute preclinical research to generate decisional data packages in support of drug-discovery stage projects.

The ideal candidate will bring extensive knowledge of a wide variety of in vivo and ex vivo research methodologies and analyses and a track record of successful scientific impact in the biotechnology or pharmaceutical industry with demonstrated experience in leading and managing scientific projects from conceptualization through execution and analysis. This includes setting project goals, designing and executing on experimental strategies, managing timelines, thinking creatively of opportunities to leverage cutting-edge technologies, and coordinating with cross-functional teams to achieve milestones and deliverables.


  • Provide scientific leadership and expertise in the field of aging/rejuvenation biology and drive data analysis and interpretation to guide decision-making processes.
  • Build preclinical strategies and experimental/analytical plans for portfolio projects, leveraging internal expertise as needed.
  • Lead ex vivo biological analysis (e.g., biomarker discovery) in collaboration with Altos Hubs and cross-functional teams.
  • Execute ex vivo experiments on diverse tissues collected from in vivo studies, perform analyses, and report results.
  • Act as the scientific lead for in vivo studies and ex vivo analyses conducted at CROs.
  • Evaluate and implement new technologies and platforms to enhance the efficiency and quality of ex vivo studies.
  • Maintain detailed documentation of all studies in electronic lab notebook to ensure data integrity and traceability.
  • Follow best practices for in vivo research methodologies, including animal model selection, dosing strategies, sample collection and data collection techniques.
  • Collaborate effectively with in vivo operation teams from the IoM to enable execution of high quality in vivo studies.
  • Collaborate with cross-functional teams, including IoS, in vitro Pharmacology, Science Integration, Innovation and Insights, Drug Metabolism and Pharmacokinetics, etc. to support the development and progression of therapeutic programs.
  • Contributes to a team culture that promotes continuous improvement, ownership, professional growth, and inclusion.

Who You Are

Minimum Qualifications

  • Ph.D. in Biology, Pharmacology, or a related field plus a minimum of 6 years of relevant postgraduate experience, with at least 3+ years of relevant industry experience leading and executing preclinical research for drug discovery and biomarker discovery.
  • Ability to think independently and creatively to design experimental strategies and analysis plans and generate robust, reproducible, and generalizable results in a timely manner.
  • 3Rs-centered, welfare-oriented approach to animal-based research.
  • Strong technical expertise and hands-on experience leveraging cutting-edge technologies (e.g. spatial transcriptomics, multi-omics, in situ imaging, etc.) to generate decisional data packages.
  • Outstanding communication skills, essential for effective collaboration with internal and external collaborators.
  • Exceptional organizational and attention to detail skills, with the capacity to work autonomously as well as in a team setting.
  • Ability to troubleshoot and effectively solve problems, demonstrating resourcefulness and a high level of analytical thinking.
  • Proficient in documenting experimental design, analysis, and interpretation of data in an ELN.

Preferred Qualifications

  • Experience working across diverse therapeutic modalities, including small molecules, biotherapeutics, nucleic acid therapeutics, and gene therapy is highly desirable.
  • Strong knowledge in several biological hallmarks of age-related diseases/ deficits; including inflammation, DNA repair, epigenetic, protein homeostasis, cell health, metabolism, etc.

The salary range for Redwood City, CA:

  • Senior Scientist I: $166,000 - $228,000
  • Senior Scientist II: $190,000 - $268,000

Exact compensation may vary based on skills, experience, and location.

For UK applicants, before submitting your application:

- Please click here to read the Altos Labs EU and UK Applicant Privacy Notice (
- This Privacy Notice is not a contract, express or implied and it does not set terms or conditions of employment.


What We Want You To Know

We are a culture of collaboration and scientific freedom, and we believe in the values of diversity, inclusion and belonging to inspire innovation.

Altos Labs provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.

This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.

Altos currently requires all employees to be fully vaccinated against COVID-19, subject to legally required exemptions (e.g., due to a medical condition or sincerely-held religious belief).

Thank you for your interest in Altos Labs where we strive for a culture of scientific freedom, learning, and belonging.

Note: Altos Labs will not ask you to download a messaging app for an interview or outlay your own money to get started as an employee. If this sounds like your interaction with people claiming to be with Altos, it is not legitimate and has nothing to do with Altos. Learn more about a common job scam at