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Scientist / Senior Scientist, Computational Chemistry

Altos Labs

Altos Labs

San Diego, CA, USA · San Francisco, CA, USA
Posted on Friday, June 7, 2024

Our Mission

Our mission is to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and the disabilities that can occur throughout life.

For more information, see our website at

Our Value

Our Single Altos Value: Everyone Owns Achieving Our Inspiring Mission.

Diversity at Altos

We believe that diverse perspectives are foundational to scientific innovation and inquiry.

We are building a company where exceptional scientists and industry leaders from around the world work side by side to advance a shared mission.

Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives.

At Altos, we are all accountable for sustaining a diverse and inclusive environment.

What You Will Contribute To Altos

An exciting opportunity is available for a talented Scientist / Senior Scientist, Computational Chemistry to join the Institute of Medicine (IOM) Drug Discovery and Development Sciences team at Altos Labs.

We are seeking highly motivated, creative, and collaborative individuals who are passionate and dedicated to employing their expertise to restore cell health and reverse disease. This position will be part of a multidisciplinary team within the IOM that will develop novel therapeutic projects and pipelines at Altos. The candidate will work in a highly dynamic and cross-functional environment that requires collaboration with the Institutes of Science and will span multiple therapeutic areas and modalities. The successful candidate will have strong scientific training and experience in the biotechnology or pharmaceutical industry.


  • Develop and implement Computational Chemistry strategies and build infrastructure to support discovery programs using internal resources and external software vendors
  • Work with scientists in the IOM and at the Institutes of Science (Bay Area, Cambridge, San Diego) to initiate virtual screening campaigns and design tool molecules to explore biological pathways and mechanisms of action
  • Continuously assess computational capability and capacity needs based on the evolving pipeline at Altos
  • Represent Computational Medicinal Chemistry in multifunctional discovery project teams
  • Effective cross-functional collaboration, especially with in vitro / in vivo pharmacology, DMPK and toxicology, in the optimization of drug leads and candidates
  • Recommend, initiate, lead and champion new innovations from external, global and local sources to ensure cutting-edge science is applied to project-related issues
  • Create and foster strong partnerships with groups in the Institutes of Science and Medicine
  • Contribute to a team culture that promotes continuous improvement, ownership, professional growth, and inclusion

Who You Are

Minimum Qualifications

  • Ph.D. in Organic/Medicinal Chemistry, Computational Sciences or related areas of science with 2+ years of industry experience in Drug Discovery
  • Extensive knowledge of computational chemistry and structure-based design
  • Demonstrated track record of accomplishments, e.g., via publications, patents, and presentation in Computational Chemistry
  • Clear and influential communicator: strong influencing skills that demonstrate strong thought partnership and create effective relationships with internal and external groups and individuals
  • Demonstrated ability to partner and collaborate effectively with research teams and drug discovery functions.
  • Experience with python, open source cheminformatics packages (e.g., RDKit) and machine learning are highly desirable.

The salary range for San Francisco Bay Area, CA:

  • Scientist II: $167,000 - $242,400
  • Senior Scientist I: $202,000 - $270,000

The salary range for San Diego, CA:

  • Scientist II: $155,000 - $214,800
  • Senior Scientist I: $179,000 - $246,000

Exact compensation may vary based on skills, experience, and location.

For UK applicants, before submitting your application:

- Please click here to read the Altos Labs EU and UK Applicant Privacy Notice (
- This Privacy Notice is not a contract, express or implied and it does not set terms or conditions of employment.



What We Want You To Know

We are a culture of collaboration and scientific freedom, and we believe in the values of diversity, inclusion and belonging to inspire innovation.

Altos Labs provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.

This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.

Altos currently requires all employees to be fully vaccinated against COVID-19, subject to legally required exemptions (e.g., due to a medical condition or sincerely-held religious belief).

Thank you for your interest in Altos Labs where we strive for a culture of scientific freedom, learning, and belonging.

Note: Altos Labs will not ask you to download a messaging app for an interview or outlay your own money to get started as an employee. If this sounds like your interaction with people claiming to be with Altos, it is not legitimate and has nothing to do with Altos. Learn more about a common job scam at